Xeomin for Facial Wrinkles
Fine lines and facial creases are a natural part of aging—but for many, these signs appear sooner or more prominently than expected. Repeated facial expressions like frowning, squinting, and smiling gradually etch wrinkles into the skin, especially around the eyes and forehead.
At Mackay Vein, we offer clinically proven injectable treatments like Xeomin® to gently smooth these lines and restore a refreshed, natural-looking appearance. With a personalized approach and decades of medical experience, our team helps patients feel confident, comfortable, and in control of their aesthetic goals.

What is Xeomin?

Xeomin® (incobotulinumtoxinA) is a prescription medication used to temporarily improve the appearance of moderate to severe facial wrinkles.
As a neuromodulator, Xeomin works by gently relaxing the muscles responsible for forming these lines, helping the skin appear smoother and more refreshed. The result is a natural-looking improvement without altering untreated areas of the face.
It is FDA-approved for treating dynamic lines in the upper face, including:
Meet the Xeomin Expert
Xeomin offers a safe, nonsurgical way to soften facial expression lines and restore a smoother, more refreshed appearance. Our experienced team provides expert care and customized treatment planning to help you feel your best.
We look forward to seeing you at one of our three convenient locations in Palm Harbor, St. Petersburg, or Largo.
- Marissa Tufariello PA-C, RVT
Xeomin Results.
Click on the images to reveal how Xeomin® was able to produce these results.
How Does Xeomin® Work?
Facial expressions such as smiling, frowning, or squinting engage specific muscles. Over time, repeated movements of these muscles cause “dynamic wrinkles,” which are visible even when your face is at rest.
It’s important to note that Xeomin is highly targeted—it treats only the injected muscles and does not affect surrounding areas. This allows for a natural result that preserves your ability to express emotion and interact confidently.
- Xeomin addresses these lines at their source.
- Once injected, it temporarily blocks the nerve signals that trigger muscle contractions in the targeted area.
- As the muscle relaxes, the skin above it begins to smooth out, reducing the appearance of lines and wrinkles.
What to Expect from Xeomin Treatments
What to During your Consultation
Every Xeomin treatment at Mackay Vein begins with a detailed consultation. During your visit, you will meet with Bethany Berghoffer, PA-C, a highly trained and experienced provider.
She will evaluate your facial anatomy, discuss your goals, and determine the appropriate dosage and injection sites for optimal results.
During the procedure, patients can expect:
- Treatment to take less than 20 minutes
- Minimal discomfort, often described as a brief pinch
- Little to no downtime, with most returning to normal activities the same day
- Mild redness or swelling at the injection site may occur but generally resolves within a few hours.
Results and Duration (how long does it last):
Visible improvement often begins within 3 to 7 days following treatment, with full results typically developing by day 14.
These results usually last about 3 to 4 months, after which additional treatments may be scheduled to maintain the desired outcome.
Ready to get started with a Xeomin Injectable Consultation at Mackay Vein & Aesthetics?
Please submit the appointment request form or call us direct at 727-527-2888.
LEARN MORE IN OUR BOTOX GUIDE
Who Is a Good Candidate for Xeomin?
Xeomin is well-suited for adults who want a non-surgical solution to reduce the appearance of facial wrinkles. You may be a good candidate if you:
Are 18 years or older
Are in good general health
Have moderate to severe dynamic wrinkles (such as frown lines, forehead lines, or crow’s feet)
Are seeking a temporary facial rejuvenation treatment with no surgery or extended downtime
Contraindications
Xeomin may not be suitable for individuals who:
Are pregnant or breastfeeding
Have a known allergy to botulinum toxin or any of Xeomin’s ingredients
Have a neuromuscular condition (e.g., ALS, myasthenia gravis, Lambert-Eaton syndrome)
Have an infection at the planned injection site
Have a history of adverse reactions to other botulinum toxin products
A complete review of your medical history will be conducted during your consultation to ensure that Xeomin is appropriate and safe for you.
Frequently Asked Questions
Is Xeomin safe?
Yes. Xeomin is FDA-approved and has been studied extensively for safety and effectiveness. Our treatments are administered by a licensed medical professional using proper technique in a clinical setting. While serious side effects are rare, a full medical screening helps reduce risk and ensure safe administration.
How soon will I see results?
Most patients begin to notice improvement within a few days of treatment. Full results are typically visible within 7 to 14 days. These effects are temporary and generally last for 3 to 4 months.
Will it change the way I look?
Xeomin is designed to soften the appearance of dynamic wrinkles while preserving your natural facial expressions. We take a conservative and personalized approach to ensure a balanced, refreshed appearance without altering your natural look.
Are there risks or side effects?
The most common side effect is mild bruising at the injection site. Other potential side effects may include:
- Redness or swelling at the injection site
- Headache
- Temporary eyelid drooping (rare)
More serious side effects are uncommon but can occur, such as:
- Difficulty swallowing or breathing
- Generalized muscle weakness
- Allergic reactions, including rash, wheezing, or dizziness
These symptoms may appear hours to weeks after injection. If you experience any of these effects, contact a medical provider immediately. A full review of possible side effects and risks will be provided prior to your treatment.
Why Patients Choose Mackay Vein & Circulation Specialists
When it comes to your face, precision and experience matter. At Mackay Vein, all injectable treatments are performed with the same high standards of medical care that have defined our practice for over 30 years.
Our approach is rooted in:
- Trusted Medical Expertise: Led by board-certified vascular surgeon Dr. Edward G. Mackay, our team brings decades of clinical experience and anatomical knowledge to every treatment.
- Expert Cosmetic Care: Aesthetic services are provided by Bethany Berghoffer, PA-C, a certified Physician Assistant with specialized training in Botox®, Xeomin®, and dermal fillers. Her detail-oriented approach helps patients achieve natural-looking results safely and comfortably.
- Personalized Treatment Plans: We take the time to understand your goals and tailor each treatment to complement your unique features—never a one-size-fits-all approach.
- A Reputation for Results: Patients across St. Petersburg and the Tampa Bay area choose us for our consistent outcomes, professional integrity, and commitment to patient-centered care.
Why choose Bethany Berghoffer PA-C for your injectable treatment
Bethany, a Northern Virginia native, has been a certified Physician Assistant since 2003. With over a decade of experience at our practice and extensive training in both medical and cosmetic services—including Botox, Xeomin, and dermal fillers—Bethany is known for her thoughtful, personalized approach and skilled aesthetic touch.
Patients trust her to deliver natural-looking results while ensuring safety and comfort throughout the process.

